Most programs are managing growth without operational intelligence.
Protocols keep getting more complex. Coordinators keep leaving. And FTE requests keep landing on a CFO's desk with no data behind them. Six pressures show up in nearly every program we assess.
Increasing protocol complexity
Every new trial changes the workload math — and few sites re-run it.
Coordinator burnout and turnover
Uneven caseloads push your best coordinators out first.
Unpredictable FTE demands
Hiring requests get built on instinct, not a defensible model.
Hidden financial deficits
Divisional margins stay invisible until they're already negative.
Sponsor performance pressure
Activation and enrollment targets tighten while staffing doesn't move.
Limited operational visibility
Leadership makes portfolio calls without a live view of the site.
Four ways we can optimize your operations
Each engagement draws from the same four disciplines — led by consultants with a minimum of 15 years in clinical trial site operations.
Workforce Transformation
- —Staff-to-trial alignment
- —FTE modeling & hiring justification
- —Coordinator role optimization
Site Digital Transformation
- —Implementation of TRIALNAV OASIS™
- —Real-time dashboards & reporting
- —Protocol complexity modeling
Process Improvement
- —GAP & SWOT analysis
- —Workflow standardization
- —Portfolio & governance optimization
Special Area Builds
- —Therapeutic area growth strategy
- —Sponsor-specific trial readiness
- —High-acuity specialty team modeling
A 4-week path from diagnosis to a defensible plan.
Three phases, run in sequence, each building the evidence base the next one needs.
Diagnostic
- Portfolio mapping
- Staffing structure review
- Financial baseline
- Protocol complexity input
Modeling
- FTE variance analysis
- Workload balancing scenarios
- Margin and ROI forecasting
Strategic Alignment
- Staffing realignment plan
- Governance recommendations
- Growth strategy
- Executive roadmap delivery
Not another slide deck of recommendations.
Traditional advisory work stops at a report. Ours ships with the model behind it.
| Aspect | Traditional Consultants | Muriera Solutions + OASIS™ |
|---|---|---|
| Experience | Often project-based or therapeutic advisory | VP-level, scaled multi-site oncology and non-oncology research networks |
| Insight | Retrospective analysis, generic benchmarking | Real-time protocol complexity scoring, FTE modeling, dashboards |
| Tools | Excel or static reports | AI-powered TRIALNAV OASIS™, scenario simulation |
| Deliverables | Recommendations only | Full operational assessment, FTE model, 12–24 month roadmap |
What programs typically see.
Typical improvement in staffing efficiency after a full engagement.
Defensible FTE hiring requests
Reduced coordinator burnout
Faster trial activation timelines
Transparent divisional financial performance
Sustainable research growth
25+ years running the programs she now advises.
Brenda Muriera is a senior clinical research operations consultant with 25+ years of progressive leadership experience transforming academic medical centers, health systems, and global research technology platforms — scaling oncology research programs and advising C-suite executives on workforce strategy and trial optimization.
She helped build and scale clinical research programs across a network spanning more than 10 states, supporting a portfolio of over 1,000 clinical trials and growing annual research revenue to more than $20 million. Her experience spans executive business development at IQVIA, clinical trial implementation consulting for integrated delivery systems, and more than a decade leading multicenter Phase I–III oncology trials at leading academic medical centers and health systems, including UT MD Anderson Cancer Center, CommonSpirit Health, Banner Health, UT Health Science Center, Cancer Treatment Centers of America, and Baylor College of Medicine.
In 2021, she founded TRIALNAV, LLC and developed TRIALNAV OASIS™—a real-time, AI-powered scoring platform that powers the assessment model featured on this page, helping research organizations evaluate readiness, identify operational gaps, and strengthen clinical trial performance.
Let's find out what your baseline program acuity score actually is.
A 30-day diagnostic starts with a 30-minute call. No deck, no pitch — just a look at where your program stands.